Parthenolide Induces Apoptosis in Glioblastomas Without Affecting NF-κB
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چکیده
منابع مشابه
VGB3 Induces Apoptosis by Inhibiting Phosphorylation of NF-κB p65 at Serine 536 in the Human Umbilical Vein Endothelial Cells
Background and objectives: Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) inhibition results in an increase in apoptosis. It has been demonstrated that NF-κB subunit p65 phosphorylation at the IκB kinase phosphorylation site serine 536 (Ser536) is essential for the NF-κB nuclear translocation and activation. Therefore, NF-κB can be downregulated by suppressing its phosph...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2008
ISSN: 1347-8613,1347-8648
DOI: 10.1254/jphs.sc0060164